PRODUCTS SOLD ON PEPTIDESLABUK.COM ARE FOR RESEARCH PURPOSES ONLY AND ARE NOT FOR HUMAN OR VETERINARY USE.
£28.99 – £89.99Price range: £28.99 through £89.99
Premium MOTS-c peptide for UK research labs. ≥99% purity, HPLC verified with full COA.
Available in 10mg and 40mg dosages. Same day dispatch for UK and international orders. Trusted by research institutions for metabolic and mitochondrial studies. In stock.




MOTS-c is a 16-amino-acid mitochondrial-derived peptide (MDP) that has emerged as a critical research tool in metabolic science and longevity studies. As one of the few peptides encoded directly by mitochondrial DNA, this compound offers researchers unique opportunities to investigate cellular energy regulation, metabolic adaptation and mitochondrial signalling pathways. UK laboratories and research institutions increasingly source high-purity MOTS-c for advanced studies examining how cells maintain energy balance and respond to metabolic stress.
Available Dosages: 10mg | 40mg
✅ ≥99% Purity – HPLC Verified
✅ COA Provided – Batch-specific documentation
✅ Third-Party Tested – Mass spectrometry confirmed
✅ In Stock – Fast UK dispatch
| Parameter | Specification |
|---|---|
| Purity | ≥99% (HPLC and MS verified) |
| Form | White lyophilised powder |
| Sequence | Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg |
| Molecular Weight | 2,174.52 g/mol |
| Solubility | Sterile water, 0.1% acetic acid |
| Storage (powder) | -20°C (stable 24+ months) |
| Storage (reconstituted) | 2-8°C (use within 2-4 weeks) |
| Available Sizes | 2mg, 5mg, 10mg, 20mg, 50mg |
This mitochondrial-derived peptide is extensively utilized in scientific investigations focusing on:
Metabolic Research: Studies examining cellular energy production, glucose metabolism pathways and AMPK-dependent signalling mechanisms frequently incorporate MOTS-c into experimental protocols. Research teams investigating metabolic homeostasis and nutrient-sensing pathways value this compound for its role in mitochondrial communication.
Cellular Ageing and Longevity Studies: The peptide’s unique mitochondrial origin makes it particularly relevant for researchers exploring age-related metabolic decline, oxidative stress responses and cellular resilience mechanisms. Laboratory work examining how mitochondrial function influences long-term cellular health often includes this compound in comparative analyses.
Exercise Physiology Research: Scientific teams studying metabolic adaptation to physical stress, muscle tissue energy utilization and endurance-related cellular responses utilize MOTS-c to understand how mitochondria regulate performance under varying metabolic demands.
Stress Response Mechanisms: Investigations into how cells adapt to metabolic challenges, including thermal stress, caloric restriction models and oxidative pressure, frequently feature this peptide as a key research variable.
Verified High Purity: Each batch undergoes rigorous HPLC and mass spectrometry analysis to guarantee ≥99% purity, ensuring consistent, reproducible results across multiple experimental models. Third-party certificates of analysis (CoA) are provided with every order.
Multiple Dosage Options: Whether your protocol requires 2mg for preliminary studies or 50mg for extensive research programs, we supply precise dosages to match your experimental needs. All sizes maintain identical purity standards.
Research-Grade Quality: Manufactured under strict laboratory conditions following GMP guidelines, our products meet the exacting standards required for peer-reviewed research and institutional studies.
Reliable Solubility and Stability: The lyophilised formulation ensures excellent reconstitution properties and predictable behaviour in controlled laboratory environments, simplifying protocol integration and reducing experimental variability.
UK-Based Support: Fast domestic shipping, knowledgeable customer service and compliance with UK research standards. Orders dispatched same day with tracked delivery.
Reconstitution Protocol:
Storage Requirements:
When you purchase research-grade MOTS-c from us, you receive:
✓ Batch-Specific Certificate of Analysis – WHich can be verified directly via portal
✓ HPLC Chromatogram – Purity verification data
✓ Mass Spectrometry Results – Molecular weight confirmation
✓ Sterility Testing Report – Endotoxin level data
✓ Reconstitution Guidelines – Protocol recommendations
✓ Technical Support – Research guidance available
| Feature | MOTS-c | Humanin | SS-31 |
|---|---|---|---|
| Origin | Mitochondrial DNA | Mitochondrial DNA | Synthetic |
| Amino Acids | 16 | 21-24 | 4 |
| Primary Research Focus | Metabolic regulation | Neuroprotection | Mitochondrial protection |
| AMPK Activation | Yes | Limited | No |
| Stability | Excellent | Good | Excellent |
| Common Dosage (research) | 5-10mg | 10-20mg | 1-5mg |
Many researchers combine MOTS-c with other mitochondrial peptides for comprehensive metabolic studies. Contact us for guidance on multi-peptide research protocols.
To reconstitute MOTS-c 10mg, add 1-2ml of sterile water or 0.1% acetic acid directly to the lyophilised powder, creating a 5-10 mg/mL solution. Use gentle swirling rather than shaking. Allow the vial to reach room temperature before opening to prevent condensation. Once dissolved, the solution can be further diluted to your required working concentration. Aliquot immediately if storing at -80°C to avoid repeated freeze-thaw cycles.
Research dosage varies significantly depending on experimental models and protocols. In-vitro studies commonly use concentrations between 1-100 μM. For animal models, published research indicates dosages ranging from 5-15 mg/kg, though specific protocols should be developed based on your research objectives. Always consult relevant literature and institutional guidelines when establishing dosage parameters for your specific investigation.
You’re in the right place. We supply research-grade MOTS-c with full certification to UK laboratories and research institutions. Every order includes a batch-specific Certificate of Analysis (CoA), HPLC chromatogram, mass spectrometry verification and endotoxin testing results. Our ≥99% purity standard and cold-chain shipping ensure your peptide arrives in optimal condition with complete traceability for your research documentation.
MOTS-c and Humanin are both mitochondrial-derived peptides but serve different research applications. MOTS-c primarily focuses on metabolic regulation, AMPK activation and glucose homeostasis, making it ideal for metabolic syndrome and energy metabolism studies. Humanin is predominantly used in neuroprotection research, cellular survival pathways and age-related cognitive decline investigations. Many researchers use both peptides in comparative studies to examine different aspects of mitochondrial signalling.
Once reconstituted in sterile water or dilute acetic acid, MOTS-c maintains stability for 2-4 weeks when stored at 2-8°C. For extended storage, create single-use aliquots and freeze at -80°C immediately after reconstitution. Frozen aliquots remain stable for several months, though optimal practice is to reconstitute fresh peptide for each experimental series. Avoid repeated freeze-thaw cycles which can degrade peptide integrity and reduce experimental consistency.
Yes, MOTS-c is legal to purchase in the UK exclusively for legitimate scientific research conducted in licensed laboratory facilities. It must be handled by qualified researchers and used only for approved research applications. This compound is not approved for human consumption, therapeutic use or any application outside controlled research environments. Purchasers must ensure compliance with institutional ethics guidelines and UK regulations governing research chemicals.
Research-grade mitochondrial peptides should have a minimum purity of ≥98%, though ≥99% is strongly preferred for metabolic and cellular studies where precision is critical. Lower purity products may contain contaminants that interfere with AMPK signalling assays, glucose uptake measurements or other sensitive metabolic analyses. Always request HPLC chromatograms and mass spectrometry verification to confirm both purity and molecular identity before incorporating into experimental protocols.
Yes, MOTS-c is widely used in cell culture research examining metabolic pathways, mitochondrial function and cellular stress responses. Typical working concentrations in cell culture range from 1-100 μM depending on cell type and experimental objectives. The peptide demonstrates excellent solubility in standard culture media and maintains stability under normal incubation conditions. Ensure sterile reconstitution and filtration through 0.22μm filters before adding to cell cultures.
The primary difference lies in the counter-ion salt form used during peptide synthesis. MOTS-c acetate and trifluoroacetate (TFA) forms are both acceptable for research, though acetate is generally preferred as TFA can occasionally interfere with certain assays or exhibit mild cellular toxicity at very high concentrations. Both forms contain the identical active peptide sequence. Reputable suppliers clearly indicate which salt form is supplied in their specifications.
Orders are typically dispatched same day of confirmation. Standard UK delivery takes 1-2 working days via tracked courier services. All shipments are packaged carefully to maintain peptide integrity during transit. Express next-day delivery options are available for urgent research requirements. International shipping is also available to all countries, though delivery times vary by destination and customs processing.
Available Dosages: 10mg | 40mg
Dispatch: Same Day
Delivery: 1-2 working days (UK)
Bulk Discounts: Available for institutional orders
Ensure your metabolic and mitochondrial research benefits from verified purity, comprehensive documentation and reliable UK delivery.
This product is supplied strictly for laboratory research purposes only, including in-vitro studies, metabolic investigations and mitochondrial function analysis. Not for human consumption or therapeutic use. Must be handled by qualified researchers in licensed facilities in accordance with UK regulations and institutional guidelines. By purchasing, you confirm acquisition solely for legitimate scientific research.
Research Excellence | Third-Party Verified | Trusted by UK Institutions




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